It's not clear from the wiki what the "strangely unsatisfying without flesh." result is from, but I am getting it with Ghoultouched, which is the probably trigger (EDIT: and not getting it with Ghoultouched turned off, so that's almost certainly it):
You kick back and drain the goblet. The liquid within, unsurprisingly, tastes like you just got punched in the mouth.
It's not filling at all, but a strange energy seems to hum back and forth between you and the goblet.
You learned a new Technique: Pouring Blood
It seems strangely unsatisfying without the flesh attached. Ah well, more to do later.
From podcast hints, there's definitely a thing or two more to find. No change with full (40/40) hunger, with Ghoul Bite and Call to Feast in deck, and Ghoultouched active. Maybe we need to do something different with eating people after getting the above message?
EDIT: Nothing with vampire shirt on.
Nothing while eating a meaty haunch with goblet equipped.